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BIO Pox

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VARICELLA VACCINE, LIVE I.P.BIO POX™

DESCRIPTION :

Bio PoxTM is indicated for active immunization against Varicella virus (Chicken Pox) of healthy subjects with no history of Varicella infection and susceptible healthy close contacts. Bio Pox™ meets the specifications of Indian Pharmacopoeia.

[/vc_column_text][/vc_column][vc_column width=”1/3″][vc_single_image image=”3961″ img_size=”full” alignment=”center”][/vc_column][/vc_row][vc_row el_class=”product-box”][vc_column width=”1/3″][vc_single_image image=”3346″ img_size=”24×24″][vc_column_text]COMPOSITION

Each single dose (0.5 ml) of reconstituted Bio PoxTM vaccine contains:

• ?2000 plaque forming units (PFU) of live attenuated Varicella virus (OKA strain) propagated in MRC-5 human diploid cell culture.
• Excipients: KH2PO4 – 0.25 mg, K2HPO4 – 0.6 mg, L-monosodium glutamate – 0.4 mg, EDTA – 1 mg, Sucrose – 37.5 mg, Human Normal Albumin – 5 mg, Polygeline (Haemaccel(R)) – 5 mg.[/vc_column_text][/vc_column][vc_column width=”1/3″][vc_single_image image=”3353″ img_size=”24×24″][vc_column_text]DOSAGE AND ADMINISTRATION

• Reconstitute Bio PoxTM with the entire content of the vaccine diluent (sterile water for injection I.P.) provided with the vaccine. Shake gently for full reconstitution. Each dose (0.5ml) shall be injected immediately after reconstitution by subcutaneous route. Alcohol or other disinfecting agent must be allowed to evaporate from the site of injection before immunization as they may inactivate the vaccine.
• Bio PoxTM is recommended for active immunization of healthy subjects of 1 to 12 years of age.
• IAP (Indian Academy of Pediatrics), recommends1 1st dose at 15 months or older, 2nd dose at 4-6 years (can be given 3 months after 1st dose). Catch-up vaccination in children, below 13 years – 2 doses 3 months apart, 13 years or more – 2 doses at 4-8 weeks apart.
• As per WHO position paper2 on varicella vaccine, two doses induce higher effectiveness and should therefore be recommended in countries where the programmatic goal is, in addition to decreasing mortality and severe morbidity, to further reduce the number of cases and outbreaks.

[/vc_column_text][/vc_column][vc_column width=”1/3″][vc_single_image image=”3346″ img_size=”24×24″][vc_column_text]CONTRA-INDICATIONS

• Vaccination is contra-indicated during pregnancy and pregnancy should be delayed for 4 weeks after vaccination. Termination of pregnancy is not indicated if vaccination was carried out inadvertently during pregnancy.
• Ongoing acute or chronic illness like fever, severe infection, persistent diarrhoea, vomiting e.t.c.
• Immuno deficient status/immuno suppressive therapy.
• There is no data regarding use in nursing women.
• Hypersensitivity to any component of the vaccine.

[/vc_column_text][/vc_column][/vc_row][vc_row el_class=”product-box”][vc_column width=”1/3″][vc_single_image image=”3352″ img_size=”24×24″][vc_column_text]POSSIBLE SIDE EFFECTS

• Reaction to vaccination generally consists of localized injection site reaction (pain, swelling, redness) and systemic reaction (fever, skin rash, headache, fatigue, vomiting, cough) which are generally relieved spontaneously after one or two days.
• Interspersed rash or blebs may appear to few recipients probably within two weeks after vaccination. No special treatment is necessary. Symptomatic treatment may be helpful in case of need.
• As with any vaccine, there is a possibility that large scale use of the vaccine could reveal adverse reactions not observed in clinical trial.

[/vc_column_text][/vc_column][vc_column width=”1/3″][vc_single_image image=”3353″ img_size=”24×24″][vc_column_text]STORAGE AND SHELF LIFE

Store between +2° to +8°C and protect from light. The shelf life of the vaccine is 2 years, if stored at recommended storage conditions. The lyophilized vaccine is not affected by freezing, stability is even better at lower temperatures.

[/vc_column_text][/vc_column][vc_column width=”1/3″][vc_single_image image=”3346″ img_size=”24×24″][vc_column_text]PRESENTATION

Single dose freeze dried vaccine, vaccine diluent (sterile water for injection I.P.) and disposable syringe as combipack.

[/vc_column_text][/vc_column][/vc_row][vc_row el_class=”product-box”][vc_column width=”1/3″][vc_single_image image=”3346″ img_size=”24×24″][vc_column_text]CLINICAL TRIALS

Bio PoxTM was found to be safe and immunogenic in children against VZV infection3, 4.

[/vc_column_text][/vc_column][vc_column width=”1/3″][vc_single_image image=”3353″ img_size=”24×24″][vc_column_text]REFERENCES

• Indian Academy of Pediatrics (IAP) Recommended Immunization Schedule for Children Aged 0 through 18 years – India, 2016 and updates on Immunization.
• Varicella and herpes zoster vaccines : WHO position paper weekly epidemiological record, No. 25, 2014, 89, 265-288.
• Phase-I, open, unicentric clinical trial for evaluation of safety of varicella vaccine, Live (I.P.) – Sharma et. al. (2014) Biotechnology International 7 (1) : 26-34.
• Safety and immunogenicity of Bio-PoxTM, a live varicella vaccine (OKA Strain) in Indian Children: A comparative multicentric, randomized phase II/III clinical trial – Dubey et. al. Human vaccines & Immuno therapeutics 2017, Vol 13, No. 9, 2032-2037.

[/vc_column_text][/vc_column][vc_column width=”1/3″][/vc_column][/vc_row][vc_row][vc_column][vc_column_text]BIO POX

PPD-Bio POX

SmPC-BIO POX[/vc_column_text][/vc_column][/vc_row]

362 replies on “BIO Pox”

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The Bio Pox vaccine seems like a reliable option for varicella prevention, especially with its compliance to Indian Pharmacopoeia standards. If you’re looking to create professional visual content for educational or medical purposes, Motion Control AI can help bring your ideas to life with intelligent motion tracking technology. Check out motion control 3.0 to explore how motion control 3.0 can elevate your video projects.

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The detailed composition and dosage instructions for Bio Pox are very helpful for healthcare providers. It’s interesting to see how the vaccine is formulated with specific excipients to ensure stability. By the way, for those interested in interactive music creation, you might enjoy the gesture synth, a free web-based instrument that uses hand tracking to control sound.

The article specifies that Bio Pox™ is indicated for active immunization against Varicella virus in healthy subjects with no history of infection. For those seeking general entertainment rather than medical details, you might check watch fmovies for film options. The vaccine’s composition includes live attenuated virus and several excipients for stability.

It’s interesting to read about the specific composition of the Bio Pox vaccine, including ingredients like sucrose and human normal albumin; I always appreciate learning about the detailed science behind medical products. Thinking about the careful formulation of such vaccines reminds me of the many choices involved in creative endeavors, much like how one might approach using a choicer voicer dub maker to blend different audio elements. It’s truly impressive how much goes into ensuring safety and efficacy.

It’s helpful that the page specifies allowing alcohol or disinfectant to evaporate before injection, since those agents can inactivate the live attenuated vaccine — a detail easy to overlook in practice. The WHO note about two doses inducing higher effectiveness is also a good point for parents planning catch-up vaccination.

It’s useful that Bio Pox is specifically described for healthy, varicella-susceptible individuals and their close contacts. Mentioning its compliance with Indian Pharmacopoeia specifications also provides important context for its intended use.

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Bio Pox™ is clearly positioned for healthy, susceptible individuals and close contacts without a history of varicella infection. It’s also useful to see that the vaccine meets Indian Pharmacopoeia specifications.

Just came across BIO Pox™ — a reliable, IP-compliant varicella vaccine for active immunization against chickenpox in healthy children aged 1–12 years. Its OKA strain formulation (≥2000 PFU/dose), precise dosing guidance per IAP & WHO recommendations, and clear contraindications make it a trusted choice for pediatric vaccination programs. The site offers comprehensive product details, storage instructions, and safety information — all well-organized and clinically relevant. For professionals seeking evidence-based, locally approved vaccinology resources, Bio-Med Vet’s platform is highly informative. Learn more here:
BIO Pox – Bio-Med Vaccinology

Bio Pox™ is clearly positioned for healthy individuals without prior varicella infection, as well as susceptible close contacts. It’s also useful to see that the vaccine meets Indian Pharmacopoeia specifications.

It’s useful that Bio Pox™ is specifically indicated for healthy, susceptible individuals and close contacts with no prior varicella infection. Noting its compliance with Indian Pharmacopoeia specifications also adds important context for its quality standards.

Bio Pox™ is clearly positioned for healthy individuals without prior varicella infection, as well as susceptible close contacts. It’s also useful to see that the vaccine meets Indian Pharmacopoeia specifications.

It’s useful to see Bio Pox™ presented for both healthy individuals without prior varicella infection and susceptible close contacts. Mentioning its compliance with Indian Pharmacopoeia specifications also adds important context about the vaccine’s standards.

Bio Pox™ is clearly positioned for healthy individuals without prior varicella infection, as well as susceptible close contacts. Noting that it meets Indian Pharmacopoeia specifications adds useful context about its standards and intended use.

It’s useful to see Bio Pox™ presented for both healthy individuals without prior varicella infection and susceptible close contacts. Mentioning its compliance with Indian Pharmacopoeia specifications also provides important context for the vaccine’s standards.

Bio Pox™ is clearly positioned for healthy individuals without prior varicella infection, as well as susceptible close contacts. It’s also useful to note that the vaccine meets Indian Pharmacopoeia specifications.

It’s helpful to see Bio Pox™ identified for healthy individuals without prior varicella infection as well as susceptible close contacts. Mentioning compliance with Indian Pharmacopoeia specifications also provides useful context for the vaccine’s standards.

Bio Pox™ is a useful addition to varicella prevention, particularly for healthy individuals without prior infection and susceptible close contacts. It’s also helpful to see that the vaccine meets Indian Pharmacopoeia specifications.

Bio Pox™’s focus on active immunization for healthy, susceptible individuals and close contacts is especially relevant for preventing chickenpox transmission. It’s also useful to note that the vaccine meets Indian Pharmacopoeia specifications.

Bio Pox™ is clearly positioned for healthy individuals without prior varicella infection, including susceptible close contacts. It’s also useful to see that the vaccine meets Indian Pharmacopoeia specifications.

Bio Pox™ is clearly positioned for healthy individuals without prior varicella infection, including susceptible close contacts. It’s also useful to note that the vaccine meets Indian Pharmacopoeia specifications.

Bio Pox™ is clearly positioned for healthy individuals without prior varicella infection, including susceptible close contacts. It’s also useful to note that the vaccine meets Indian Pharmacopoeia specifications.

It’s useful that Bio Pox™ is presented for both healthy individuals without prior varicella infection and susceptible close contacts. Noting its compliance with Indian Pharmacopoeia specifications also adds helpful context for readers evaluating the vaccine.

It’s helpful that Bio Pox is described for both healthy individuals without prior varicella infection and susceptible close contacts. Noting its compliance with Indian Pharmacopoeia specifications also adds useful context for healthcare professionals.

It’s useful that Bio Pox™ is indicated not only for healthy individuals without prior varicella infection but also for susceptible close contacts. Mentioning its compliance with Indian Pharmacopoeia specifications adds important context for healthcare professionals evaluating the vaccine.

It’s useful that Bio Pox™ is specifically indicated for healthy individuals without prior varicella infection and susceptible close contacts. Noting its compliance with Indian Pharmacopoeia adds important context for quality and regulatory standards.

The note that two doses can offer higher effectiveness is important, but the page would be easier to use if the age-based schedule and catch-up intervals were presented beside that rationale in a compact table. Any visual medication materials should retain exact clinical wording; InpaintingAI can remove authorized temporary text from an image, not change medical information.

Bio Pox™’s focus on active immunization for healthy, susceptible individuals and close contacts is especially relevant for preventing varicella transmission. It’s also useful to note that the vaccine meets Indian Pharmacopoeia specifications.

Bio Pox™ is clearly positioned for healthy, susceptible individuals and close contacts without a prior history of varicella infection. It’s also useful to see that the vaccine meets Indian Pharmacopoeia specifications.

It’s useful to see Bio Pox™ presented specifically for healthy, susceptible individuals and close contacts with no prior varicella infection. Mentioning its compliance with Indian Pharmacopoeia also adds important context for evaluating the vaccine’s standards.

Wait, the excerpt says it meets Indian Pharmacopoeia specs but lists the OKA strain propagated in MRC-5 cells—is that the same formulation used in other markets or a locally adapted version? Also curious why the buffer excipients are spelled out so specifically here when most product pages skip that level of detail.

Interesting to see the specific composition broken down, especially the 2000 PFU of the OKA strain and the note about letting alcohol evaporate before injection since it can inactivate the vaccine. That’s a detail most people wouldn’t think about. Also, if you’re ever curious about your own facial structure, this face shape detector is a handy little tool to check.

It’s useful to see Bio Pox™ clearly positioned for healthy, varicella-susceptible individuals and close contacts. Noting that it meets Indian Pharmacopoeia specifications also adds important context for its quality and regulatory standards.

Bio Pox™ is clearly positioned for healthy individuals without prior varicella infection, including susceptible close contacts. It’s also useful to note that the vaccine meets Indian Pharmacopoeia specifications.

Reading the composition section, I noticed the vaccine uses the OKA strain propagated in MRC-5 human diploid cells with a minimum of 2000 PFU per dose, which is a detail I don’t usually see spelled out so plainly on product pages. The indication is specifically for healthy subjects with no prior varicella history and susceptible close contacts, so it’s clearly not aimed at immunocompromised people. I do wonder how the potassium phosphate and monosodium glutamate excipients factor into stability once reconstituted, since that’s often where live vaccines get tricky. Overall it’s a fairly bare-bones product description, but the pharmacopoeia compliance note is at least a useful reference point.

The composition section mentions ≥2000 PFU of the OKA strain propagated in MRC-5 cells — do you know what the actual measured potency is at release versus at expiry, since live attenuated vaccines tend to lose titer over shelf life? Also curious whether the Indian Pharmacopoeia spec sets a minimum PFU threshold that differs from WHO requirements for varicella vaccines. And with the potassium phosphate buffers listed as excipients, is there any stabilizer like gelatin or hydrolyzed porcine gelatin in the final formulation, or was that deliberately left out?

Good to see a dedicated page for BIO Pox with the relevant R&D and quality management context up front rather than buried in a brochure. For buyers comparing veterinary vaccines, having the product page also clearly link to enquiry and local dealer information saves a lot of back-and-forth emails.

It’s useful that Bio Pox™ is specifically indicated for healthy individuals without prior varicella infection as well as susceptible close contacts. Noting its compliance with Indian Pharmacopoeia also provides important context for the product’s standards.

It’s useful to see Bio Pox™ presented for healthy individuals without prior varicella infection, as well as susceptible close contacts. Mentioning its compliance with Indian Pharmacopoeia specifications also adds important context for evaluating the vaccine.

It’s helpful that Bio Pox™ is specifically described for healthy individuals without prior varicella infection as well as susceptible close contacts. Noting its compliance with Indian Pharmacopoeia specifications also adds useful context for practitioners evaluating the vaccine.

BIO Pox 的产品线看起来覆盖人和动物疫苗两个方向，这种双轨布局在兽用疫苗企业里并不常见。比较好奇产品的适用范围和在不同地区注册的差异，如果页面能补上适应症和规格说明会更实用。

It’s helpful that Bio Pox™ is described for both healthy individuals without prior varicella infection and susceptible close contacts. Noting its compliance with Indian Pharmacopoeia specifications also adds useful context for evaluating the vaccine.

Came across this post today and it was well worth the read. The section on “BIO Pox” was especially helpful. Finding the hidden skulls in Kaiju Alpha takes forever without a map; kaijualpha.com has the complete location guide.

Bio Pox™ is presented as a live varicella vaccine for healthy individuals without prior chickenpox infection, including susceptible close contacts. It is also notable that the product meets Indian Pharmacopoeia specifications.

I get why a vet product page would list contraindications so carefully, but the line about avoiding alcohol or disinfectant at the injection site made me think about how often people skip basic prep steps. I had a similar experience when I started reading up on vaccines and health policy—I wanted a simple way to see where I actually stood on related public-health tradeoffs, so I tried a free 12 axes political test that broke my views into separate axes instead of one label. It helped me separate “personal choice” from “public risk” arguments without getting stuck in a single left-right frame.

Bio Pox™’s focus on active immunization for healthy, susceptible individuals and close contacts is particularly relevant for preventing varicella transmission. It is also useful to see that the vaccine meets Indian Pharmacopoeia specifications.

It’s useful that Bio Pox™ is presented for healthy individuals without prior varicella infection as well as susceptible close contacts. Noting its compliance with Indian Pharmacopoeia adds important context for its intended clinical use.

Bio Pox™’s focus on active immunization for healthy individuals without prior varicella infection, as well as susceptible close contacts, is clearly outlined. It’s also useful to note that the vaccine meets Indian Pharmacopoeia specifications.

Most vaccine manufacturers bury the technical sheets behind a login, so having the range, research and quality management details visible up front is genuinely helpful for veterinarians who need to reference them. I would still like to see the product presentations here with indications and administration details for both farm and companion animals.

It’s useful to see Bio Pox™ clearly positioned for healthy individuals without prior varicella infection, including susceptible close contacts. Noting its compliance with Indian Pharmacopoeia specifications also adds important context for vaccine quality and standards.

It’s useful to see Bio Pox™ clearly positioned for healthy, varicella-susceptible individuals and close contacts, with compliance to Indian Pharmacopoeia specifications. Including guidance on eligibility and vaccination timing would make this product information even more practical.

Bio Pox™ is clearly positioned for healthy individuals without prior varicella infection, as well as susceptible close contacts. Noting that it meets Indian Pharmacopoeia specifications adds useful context regarding its quality standards.

It’s useful to see Bio Pox™ identified for healthy individuals without prior varicella infection, as well as susceptible close contacts. Mentioning compliance with Indian Pharmacopoeia specifications also provides important context for the vaccine’s quality standards.

Bio Pox™’s indication for healthy individuals without prior varicella infection, including susceptible close contacts, is clearly stated. It is also useful to note that the vaccine meets Indian Pharmacopoeia specifications.

Bio Pox™ is clearly positioned for healthy, susceptible individuals and close contacts without a prior history of varicella infection. It’s also useful to note that the vaccine meets Indian Pharmacopoeia specifications.

Bio Pox™’s focus on active immunization for healthy people without prior varicella infection, including susceptible close contacts, is clearly explained. It’s also useful to note that the vaccine meets Indian Pharmacopoeia specifications.

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